Alleviation of acquired stuttering with human centremedian thalamic stimulation.

Treatment of motor and non-motor features of Parkinson's disease with deep brain stimulation.

Deep brain stimulation (DBS) is an established procedure for the symptomatic treatment of Parkinson's disease. Several deep brain nuclei have been stimulated, producing a wide range of effects on the motor and non-motor symptoms of Parkinson's disease. Long-term, high-quality evidence is available for stimulation of the subthalamic nucleus and globus pallidus internus, both of which uniformly i...

Author's response to reviews Title: Aggravated stuttering following subthalamic deep brain stimulation in Parkinson's disease - two cases Authors:

Deep brain stimulation alleviates parkinsonian bradykinesia by regularizing pallidal activity.

Deep brain stimulation (DBS) of the basal ganglia can alleviate the motor symptoms of Parkinson's disease although the therapeutic mechanisms are unclear. We hypothesize that DBS relieves symptoms by minimizing pathologically disordered neuronal activity in the basal ganglia. In human participants with parkinsonism and clinically effective deep brain leads, regular (i.e., periodic) high-frequen...

Thalamic stuttering: a distinct clinical entity?

A 38-year-old right-handed male with no history of speech or language problems presented with neurogenic stuttering following an ischaemic lesion of the left thalamus. He stuttered severely in propositional speech (conversation, monologue, confrontation naming, and word retrieval) but only slightly in non-propositional speech (automatic speech, sound, word and sentence repetition, and reading a...

P24: Minimally Conscious State Improvements with Thalamic Ventralis Intermedius Nucleus Stimulation after Severe Traumatic Brain Injury

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